Examining the Risk of Alzheimer's Disease and Related Dementia Among People with Spinal Cord Injury: A Mixed-Methods Study Comparing Veterans and Civilians

Abstract

Traumatic spinal cord injury (TSCI) is often associated with life-long debilitating consequences that negatively impact quality of life. With advances in healthcare, life expectancy for people afflicted with TSCI has increased substantially. While aging is the main risk factor for Alzheimer's Disease and Related Dementia (ADRD), new evidence on higher likelihood for developing ADRD after TSCI is emerging. In particular, during our recent study of commercially insured individuals with TSCI in the United States, we found that people with TSCI had an elevated risk for ADRD compared to a matched cohort of the general population without disability. Yet there is a scarcity of epidemiological studies examining associations between TSCI and ADRD and use of services that may ameliorate this risk. Given that the Veterans Health Administration (VA) is known as the largest and most comprehensive system of care in the U.S., it is imperative to examine the composite of protective effects conferred by therapeutics and lifestyle on incident ADRD.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2022
Accession Number
AD1194079

Entities

People

  • Elham Mahmoudi

Organizations

  • Board of Regents of the University of Michigan

Tags

DTIC Thesaurus Topics

  • Alzheimer Disease
  • Biomedical Research
  • Data Analysis
  • Dementia
  • Diseases
  • Governments
  • Health Services
  • Humanities
  • Institutional Review Board
  • Local Governments
  • Management Personnel
  • Medical Personnel
  • Professional Development
  • Quality Of Life
  • Spinal Cord
  • Spinal Injuries
  • Therapy
  • United States
  • Universities

Fields of Study

  • Medicine

Readers

  • Aquatic Ecology
  • Neurotrauma and Rehabilitation Medicine.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.