Proactive Targeted Coagulation Management during Trauma and Acute Respiratory Distress Syndrome
Abstract
A targeted coagulation panel will identify specific impairments to hemostasis during organ support in the early post-trauma (72h) phase. In future conflicts demanding prolonged care in place prior to casualty evacuation, the need for advanced organ support systems to sustain life in the forward setting will be essential. Current organ support systems require administration of systemic anticoagulation to prevent bleeding/thrombotic complications related to extracorporeal blood circulation within the medical devices. However, in the setting of combat trauma systemic anticoagulation is contraindicated. Trauma-specific coagulation management guidelines and strategies for extracorporeal organ support in the combat care setting are necessary for delivery of artificial organ support in the forward setting. Objective: Investigate key biomarkers identified as drivers of coagulation derangement following trauma alone, as well as during artificial organ support alone that have not been investigated in the setting of trauma and organ support together.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2023
- Accession Number
- AD1196253
Entities
People
- Teryn R. Roberts
Organizations
- Geneva Foundation