Genomic and Biological Risk Prediction of Aggressive and Lethal Prostate Cancer in African American Men

Abstract

The purpose of this project is to develop a novel genomic/biological risk prediction approach to prostate cancer in men of African descent by identifying and developing a genomic signature that can predict for aggressive and potentially lethal prostate cancer. This project will utilize rich data from several large data sources and registries to evaluate the impact of genetic biomarkers and other clinical factors on the risk of lethal prostate cancer in men of African descent. The resulting genomic findings could help improve currently used clinical tools to identify African-descent men most likely to be at risk of lethal prostate cancer.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2022
Accession Number
AD1197106

Entities

People

  • Brandon A Mahal

Organizations

  • University of Miami

Tags

DTIC Thesaurus Topics

  • Abstracts
  • African Americans
  • Biological Markers
  • Biology
  • Biomedical Research
  • Classical Genetics
  • Clinical Trials
  • Data Analysis
  • Diseases
  • Disparities
  • Genetics
  • Genomics
  • Health Services
  • Information Science
  • Machine Learning
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Risk
  • Risk Analysis
  • Schools
  • Scientific Research
  • Universities

Readers

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  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology