Biopsy Guidance of Lung Cancer Using a Novel Electromagnetic and Optical Coherence Tomography Platform

Abstract

Early diagnosis of lung cancer is critical to patient survival. Diagnosis must be made on the microscopic level, unfortunately, low-risk bronchoscopy techniques for retrieving biopsy samples are hampered by low diagnostic yields, and trans-thoracic and surgical approaches carry higher intrinsic risk of complications. The objective of this proposal is to develop and test a steerable and electromagnetic optical coherence tomography (EM-OCT) biopsy guidance and diagnosis tool with the goal of dramatically increasing the diagnostic yield of low risk bronchoscopic based diagnosis of lung cancer. The EM-OCT guidance platform will provide large-scale computed tomography (CT), and electromagnetic (EM) guidance as well as microscopic (OCT) guidance ensuring that the catheter is positioned within the target lesion. This will better allow clinicians to target and collect biopsy specimens from tumor tissue, improving the diagnostic yield of the biopsy. We anticipate that when used in combination with CT screening, the EM-OCT guidance tool will significantly increase the early detection, diagnosis, and treatment of lung cancer and will reduce the number of high-risk surgical diagnostic and therapeutic procedures performed.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2022
Accession Number
AD1197735

Entities

People

  • Melissa J. Suter

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Accuracy
  • Biomedical Research
  • Bronchoscopy
  • Department Of Defense
  • Detection
  • Detectors
  • Disease Attributes
  • Diseases
  • Endoscopes
  • Guidance
  • Health Services
  • Lung Cancer
  • Lung Diseases
  • Medical Personnel
  • Navigation
  • Neoplasms
  • Optical Scanning
  • Smooth Muscle
  • Therapy
  • Tomography
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

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