Detecting Synthetic Opioids: Exploration of Surface-Enhanced Raman Spectroscopy and Development of Master Spectrum for Detection of Unknowns

Abstract

This effort, in support of the U.S. Department of Homeland Security, Science and Technology Directorate (Washington, DC), assessed the ability to augment current handheld Raman spectroscopic systems with surface-enhanced Raman spectroscopy substrates. The work was performed to understand pathways and analyze trace-level amounts of materials on contaminated surfaces. Additional work is reported on the construction of a unique single data element (library spectrum) that was developed with hundreds of synthetic opioid examples. The focus of this work was to assess whether the single spectrum could be used to detect the presence of an opioid even if the material was not in the systems database and had not been previously seen.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2023
Accession Number
AD1198857

Entities

People

  • Andrew J. Walz
  • Ashish Tripathi
  • Erik Emmons
  • James Myslinkski
  • Jason A Guicheteau
  • Neal Kline
  • Phillip Wilcox

Tags

Communities of Interest

  • Advanced Electronics
  • Counter WMD
  • Energy and Power Technologies
  • Sensors

DTIC Thesaurus Topics

  • Chemistry
  • Detection
  • Detectors
  • First Responders
  • Homeland Security
  • Identification Systems
  • Liquid Chromatography
  • Materials
  • Metallic Nanoparticles
  • Microscopes
  • Nanoparticles
  • Optics
  • Raman Spectra
  • Raman Spectroscopy
  • Spectra
  • Spectrometers
  • Spectroscopy

Readers

  • Analytical Chemistry
  • Defense Technology Research and Development.
  • Quantum spin resonance or Electron Paramagnetic Resonance spectroscopy.