Enriching Vitality and Compressing Risk for Alzheimer's Disease Among Aging Veterans with TBI
Abstract
The purpose of this study is to evaluate the efficacy of a novel 3-D gaming intervention (Bandit the Dolphin) on executive functions (e.g., planning), mobility (e.g., walking) and in brain biomarkers linked to risk for Alzheimer's disease. This study will also assess if playing a game that trains to the real world will increase daily activities that in turn promote the brain and body. The scope is to conduct a 12-month randomized controlled trial of individuals with chronic or moderate TBI and evaluate cognitive, physical, psychiatric, physiological, and brain function at baseline, 3-month after the game intervention or healthy aging control arm, followed by a 9-month post intervention assessment. There is no data to report for this year due to delays caused by the pandemic and HRPO approval. The most substantial progress during this reporting period is an improved Bandit the Dolphin that enhances player enjoyment and standardizes in-game training, and replacement of the arm swimmer control to a health education program shown to benefit participants in published trials without affecting study outcomes.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2022
- Accession Number
- AD1200739
Entities
People
- Michelle M. Carlson
Organizations
- Johns Hopkins University