MOTION: Moving Online Together Investigation of Neurocognition

Abstract

The goal of this study is to examine a novel, integrative mind-body movement program, Preventing Loss of Independence through Exercise (PLI), with Tai Chi for the ability to improve cognition and enhance brain connectivity in people with mild cognitive impairment (MCI) and subjective memory decline (SMD). The two mind-body interventions will also be compared with an active control, Health and Wellness Education (HWE) in a randomized controlled trial (RCT). Aim 1 will evaluate the effects of PLI and Tai Chi versus HWE, all delivered remotely via tele-health techniques, on the Alzheimer's Disease Assessment Scale - cognitive subscale (ADAS-cog). Aim 2 will evaluate the effects of the three interventions on default mode network (DMN) functional connectivity. Aim 3 will explore the association between changes in functional connectivity with changes in cognition.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2022
Accession Number
AD1200754

Entities

People

  • Linda L Chao

Organizations

  • Northern California Institute for Research and Education

Tags

Communities of Interest

  • Human Systems

DTIC Thesaurus Topics

  • Alzheimer Disease
  • Biomedical Research
  • California
  • Cognitive Impairment
  • Databases
  • Dementia
  • Department Of Defense
  • Diseases
  • Education
  • Genetics
  • Health
  • Health Care
  • Health Services
  • Instructors
  • Intervention
  • Medical Personnel
  • Neuroimaging
  • Pain
  • Parkinson'S Disease
  • Public Health
  • Quality Of Life

Fields of Study

  • Medicine
  • Psychology

Readers

  • Computer Science.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.