Supercooled Ex-Vivo Porcine VCA Preservation to Extend the Timeline Between Procurement and Transplantation and Enable Tolerance Induction to Eliminate Immunotherapy Needs and Risks

Abstract

The project aims to develop a novel technology to preserve vascular composite allografts for extended periods. This project uses a porcine model. In the second year the focus was on identifying ideal perfusion parameters and initiating transplant studies.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2022
Accession Number
AD1202127

Entities

People

  • Korkut Uygun

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Albumins
  • Anesthesia
  • Animal Structures
  • Arteries
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cold Storage
  • Composite Materials
  • Data Analysis
  • Health Services
  • Medical Personnel
  • Physicians
  • Procurement
  • Public Policy
  • Risk
  • Transplants

Readers

  • Oncology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology