Targeting DDR1 Aberrations in Metastatic ER+ Breast Cancer

Abstract

This proposal investigates the role of aberrations (overexpression and somatic mutations) in the collagen receptor DDR1 (Discoidin Domain Receptor 1) in driving endocrine resistance, metastasis, and poor prognosis in estrogen receptor positive breast cancer.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2022
Accession Number
AD1202733

Entities

People

  • Meghashyam Kavuri

Organizations

  • Baylor College of Medicine

Tags

DTIC Thesaurus Topics

  • Amplification
  • Antibodies
  • Bioluminescence
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Cell Line
  • Cell Movement
  • Cells
  • Data Sets
  • Demographic Cohorts
  • Diseases
  • Electronic Mail
  • Immunohistochemistry
  • Mammary Glands
  • Medical Personnel
  • Neoplasms
  • Proteins
  • Rna Sequence Analysis
  • Sex Glands
  • Standards
  • Xenografts

Readers

  • Immunology
  • Molecular Biology and Genetics