Development of the Anti-Inflammatory Mast Cell

Abstract

The purpose of the project is to develop a real time pre-exposure prophylactic for severe food allergies and prevent life threatening anaphylaxis. We have developed the methodology needed to generate knockout Mast cell lines that are not capable of releasing histamine or prostaglandins. We are currently working towards generating a knockin mast cell to counter the allergic response.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2023
Accession Number
AD1203262

Entities

People

  • Mary Premenko-lanier

Organizations

  • SRI International

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Allergens
  • Allergy And Immunology
  • Anaphylaxis
  • Biomedical Research
  • Cell Line
  • Cells
  • Diseases
  • Electronic Mail
  • Histamine
  • Knocking
  • Maryland
  • Mast Cells
  • Medical Personnel
  • Professional Development
  • Prostaglandin
  • Sars
  • Sequences
  • Students
  • Vaccines
  • Viruses

Readers

  • Allergy and Immunology.
  • Molecular and Cellular Biology
  • Systems Analysis and Design