Unlocking the Potential of Bacterial ParE Toxins: Developing a Blueprint for Co-Opting Molecular Time Bombs That Impact Bacterial Cell Survival

Abstract

This project aims to Unlock[ing] the potential of bacterial ParE toxins: developing a blueprint for co-optingmolecular time bombs that impact bacterial cell survival. The central problem addressed by the aims is oftreating bacterial infections with an outcome of making existing antibiotics work better, and inunderstanding a fundamental bacterial mechanism that may help bacteria become resistant. Whensuccessful, this will provide an innovative new way to control bacterial growth, including antibacterialresistant strains.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2023
Accession Number
AD1203890

Entities

People

  • Christina R Bourne

Organizations

  • University of Oklahoma

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antitoxins
  • Bacteria
  • Bacterial Infections
  • Bacteriology
  • Biological Products
  • Biomedical Research
  • Cell Physiological Processes
  • Chemistry
  • Chlamydia
  • Department Of Defense
  • Infection
  • Infectious Diseases
  • Medical Personnel
  • Microbiology
  • Microbiomes
  • Molecular Biology
  • Pathogenic Bacteria
  • Proteins
  • Students
  • Toxicity

Fields of Study

  • Biology

Readers

  • Aerial Delivery - Logistics and Supply Chain Management.
  • Microbial Pathology
  • Military History of the United States in the 20th Century.