Discovery of New Antimicrobial Compounds from Marine Actinobacteria Associated with Sponges
Abstract
This project looks at the diversity of antimicrobial-producing actinobacteria in sponges. Sponges are known to produce natural products such as antimicrobial compounds and are known to harbor actinobacteria which are a known source of antibiotics. In this project, we have collected six sponge samples by SCUBA diving and isolated 416 bacterial strains (203 from site 1, 134 from site 2, and 79 from site 3.) Of the strains from site 1, 33 were found to be gram positive and genetically analyzed. DNA sequencing of the partial 16s ribosomal RNA gene revealed that 17 of these 33 matched up to known actinobacteria. The DNA of all strains from sites 2 and 3 have been isolated and prepared for sequencing. Glycerol stocks of all identified actinomycetes will be preserved at -80C and made available for antimicrobial activity assays by AFRL
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 29, 2020
- Accession Number
- AD1204595
Entities
People
- Govind S. Nadathur