Smart Coating with Biomimetic Antimicrobial Nanostructures and Strain-Mapping Electronics for Osseointegrated Prostheses to Address Infection and Mechanical Failure Risks
Abstract
The objective is to develop a smart polymer-foil coating that can be conformally applied on the surface of the skin-penetrating abutment of the osseointegrated prosthetic implants, which simultaneously provides antimicrobial and structural-health-monitoring functionalities. The biomimetic antimicrobial nanopillar arrays on its outer surface prevent surface biofilm formation and reduce risk of superficial infection. Meanwhile, a multiplexed strain sensor arrays on its inner surface intended for conformal contact with the implant offer high sensitivity and high spatial resolution mapping of the strain distribution on the implant, providing active feedbacks to prevent implant mechanical failures. In this year, we have developed a unique process to fabricate flexible multiplexing field-effect transistors and strain sensors with high (approx. 50) gauge factors to precisely detect physiologically relevant implant strain down to 0.01 percent, based on transfer-printed high-quality single-crystalline silicon nanomembranes. A 3 by 3 multiplexing array has been fabricated. Its strain-mapping performance and functionality has been authenticated through comparison against commercial gauges and finite-element simulations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2023
- Accession Number
- AD1206975
Entities
People
- Qing Cao
Organizations
- University of Illinois Urbana–Champaign