Comparative Effectiveness of Acupuncture for Chronic Pain and Comorbid Conditions in Veterans
Abstract
Building on identified scientific gaps in the literature and our promising preliminary data, we will conduct a randomized controlled trial (RCT) of Electro-acupuncture (EA) vs. Battle Field Acupuncture (BFA) vs. Waitlist Control usual care (WLC) on 360 patients with chronic musculoskeletal pain. We will also examine the effects of baseline outcome expectancy and genetic polymorphisms on pain reduction. The overarching goal of the Personalized Electro-acupuncture vs. Auricular-acupuncture Comparative Effectiveness (PEACE) trial is to investigate EA and BFA (a form of auricular acupuncture) to guide the personalized delivery of treatment to improve pain and co-morbid symptoms. To achieve the overarching goal, the specific aims are: Specific Aim 1: To compare the effects of Electro-acupuncture (EA) vs. Battle Field Acupuncture (BFA) vs. Waitlist Control usual care (WLC) on patient-reported pain (primary outcome), physical functions, and co-morbid symptoms [fatigue, sleep disturbance, anxiety, depression, and post-traumatic stress disorder (PTSD)] among patients experiencing chronic musculoskeletal pain for three months or greater. Specific Aim 2: To determine the interaction between outcome expectancy and type of needling delivery (EA vs. BFA) on pain reduction. Specific Aim 3: To evaluate the association between specific genetic polymorphisms and patients responses to acupuncture.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2022
- Accession Number
- AD1209667
Entities
People
- Jun J Mao
Organizations
- Memorial Sloan Kettering Cancer Center