Inflammatory Processes, Emotion Regulation, and Depression in Prostate Cancer Survivors
Abstract
The period following radical prostatectomy or radiation therapy for localized prostate cancer is marked by relatively rapid changes in prostate-specific physical functioning. This can be a critical period marked by increased depression and poor adjustment for men, though substantial heterogeneity across men exists. Depression, when occurring in the context of cancer, can compromise important functional and health outcomes. However, little research has sought to examine the unfolding risk and occurrence of depression following prostate cancer treatment. A primary goal of this research is to specify and test a theoretically-driven model of how psychological and contextual vulnerabilities shape trajectories of depression in the year following prostate cancer treatment. This approach will allow for identification of which features characterize patients in whom depression is persistent and to whom intervention can be targeted, and which processes are promising targets for intervention. To date, accomplishments have included project initiation and procurement of project staff, and a focus on patient recruitment and enrollment. To date, 32 participants are enrolled Understanding of the nature and structure of depression as it is experienced by this patient group will have implications for both assessment and treatment of depression in prostate cancer patients and ultimately the efficacy of interventions aimed at reducing the intensity of that depression.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2023
- Accession Number
- AD1209670
Entities
People
- Michael A. Hoyt
Organizations
- University of California, Irvine