Enhancing Lung Injury Treatment Modalities with Nitric Oxide
Abstract
Inhaled Nitric Oxide (INO) is a selective pulmonary vasodilator delivered from compressed gas cylinders filled to 2200 pounds per square inch gauge (psig) with 800 parts per million (ppm) of Nitric Oxide (NO) in a balance of nitrogen. NO is currently FDA approved for use in term or near-term infants with hypoxemia and signs of pulmonary hypertension in the absence of cardiac disease. NO has also been shown to improve oxygenation in adults with refractory hypoxemia.Current doctrine precludes the use of NO during military aeromedical transport owing to the requirement for large, compressed gas cylinders. We performed a bench evaluation of two delivery systems that create NO from room air without the need for pressurized cylinders.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 23, 2023
- Accession Number
- AD1210239
Entities
People
- Chris Blakeman
- Dario Rodriquez
- Michael D Goodman
- Richard D Branson
Organizations
- University of Cincinnati