Sample Preparation for Proteomic Analysis of Barnacle Basal Materials

Abstract

Briefly, this method utilizes sample buffer extraction of barnacle proteins, denaturation, separation via gel electrophoresis based on molecular weight and size. Once vertical separation is achieved, gel image is obtained and protein bands are cut out at the corresponding molecular weights, cutting pattern is recorded, and in-gel digestion using trypsin is performed. This protocol requires a minimum two working days to be completed.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 11, 2023
Accession Number
AD1210840

Entities

People

  • Christopher M Spillmann
  • Dagmar H Leary
  • Eric O Mcghee
  • William J. Hervey

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Advanced Electronics
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Acetonitrile
  • Adhesion
  • Adhesives
  • Aquatic Organisms
  • Biological Sciences
  • Biology
  • Chemical Synthesis
  • Chemistry
  • Electrophoresis
  • Engineering
  • Gel Electrophoresis
  • Mass Spectrometry
  • Materials
  • Materials Science
  • Molecular Weight
  • Polymers
  • Proteins
  • Proteomics
  • Standards

Readers

  • Molecular and Cellular Biochemistry
  • Oceanography.
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Biotechnology