Familial Hypercholesterolemia in the United States: Evaluating a Centralized Cascade Screening Model to Improve Early Diagnosis
Abstract
Cascade (family) screening remains the best method to identify individuals with Familial Hypercholesterolemia. The purpose of this project is to use implementation science methods to test a centralized approach to cascade screening, similar to the most successful program in the world (Netherlands), and assess its cost-effectiveness. Our scope includes two centers in the Dallas, TX, area from which FH patients will be recruited to participate. Thus far, we are nearly complete with Aim 1 which involves assessing barriers and facilitators of cascade screening via semi-structured interviews of patients and providers. We have developed an implementation blueprint, and once these interviews are analyzed, we will then use intervention mapping to adapt the centralized cascade screening model for the US. We anticipate starting Aim 2 in the next few months. We have already begun Aim 3, which will demonstrate the cost effectiveness on cascade screening in the US.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2023
- Accession Number
- AD1211486
Entities
People
- Zahid Ahmad
Organizations
- University of Texas at Dallas