Mild Traumatic Brain Injury, Sleep, and Cardiovascular Disease: An Analysis of Military Health System Data
Abstract
Mild traumatic brain injury (mTBI) and Post-Traumatic Stress Disorder (PTSD) are important health consequences associated with military service. mTBI and PTSD share similar symptomology and sequelae, and together with comorbid sleep conditions, increase risk of coronary heart disease (CHD). This study compared 68,705 mTBI and 128,252 matched non-mTBI control patients by analyzing encounter-level data within the Military Healthcare System (MHS) between 2007-2019. Patients were followed up from study entry to one of the following occurred: CHD, death, disenrollment from the MHS, or end of the study. The primary study outcome was CHD as indicated by ICD codes. Cox proportional hazard models with time-varying covariates examined the relationship of mTBI, PTSD, and/or sleep problems to CHD incidence.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 11, 2022
- Accession Number
- AD1212233
Entities
People
- Keen S. Liew
Organizations
- Uniformed Services University of the Health Sciences