Developing a Novel Therapy for Rhabdomyolysis

Abstract

The purpose of this project is to determine the optimal dose and timing of cilastatin therapy to determine strategies to mitigate acute kidney injury (AKI), and to determine whether or not the pragmatic administration of cilastatin prevents rhabdomyolysis induced AKI (rhAKI), hyperkalemia, and mortality caused by a combat-relevant model of severe musculoskeletal trauma.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2023
Accession Number
AD1212452

Entities

People

  • Michael P. Hutchens

Organizations

  • Oregon Health & Science University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anesthesia
  • Burns
  • Cell Physiological Processes
  • Data Analysis
  • Diseases
  • Drug Therapy
  • Health Services
  • Kidney Diseases
  • Law
  • Medical Personnel
  • Military Medicine
  • Polytrauma
  • Pregnancy Complications
  • Statistical Analysis
  • Students
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Housing Policy Studies in Military Families with Privatization and Telomerase Allowance Units, Multi-Family Housing, and Telomere Lengths.
  • Neurotrauma and Rehabilitation Medicine.