Why Does Acute Postwhiplash Injury Pain Transform into Chronic Pain? Multimodal Assessment of Risk Factors and Predictors of Pain Chronification
Abstract
This project aims to find why some acute mTBI patients turn into chronic pain patients, and other do not. We recruited patients shortly afterthe accident, and assigned them to clinical, psychophysical and psychological assessment, brain MRI, EEG, and genetic tests. We thenfollowed up on the pain levels along one year. All clinical work was done in Israel, analysis was done in cooperation with our researchpartners in the US, Canada and Australia.We recruited 462 patients, 249 of them completed the first visit performed within 72 hours after the accident; 197 participants answered the3 months follow up questions, 213 answered the 6 months, and 210 answered the 12 months follow up questions. 96 participated in the 6months visit and 86 participated in the 12 months visit, of which 49 were tested in both sessions. 60 patients gave blood samples for RNAsequencing in genetics data collection. Others failed to continue with the protocol despite their initial consent and are dropouts. At thepresent time we have analyses of the specific lines in parallel, as presented below. We will continue to analyze the amalgamated data fromall line in near future.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 2021
- Accession Number
- AD1212581
Entities
People
- David Yarnitsky