Novel Evaluation of Control and Prevention Strategies for Ticks and Tick-Borne Diseases

Abstract

While Lyme disease (B. burgdorferi) is the nation's most prevalent vector-borne zoonotic disease, the increasing suite of human pathogens transmitted by the blacklegged tick, lone star tick and the recent introduction/establishment of the Asian longhorned tick in the Western Hemisphere, increases occupational health risk for soldiers training in the field, for military dependents and civilians who live, work or recreate on military installations and wild lands. In this project, wee utilized multiple approaches to assess the efficacy of new pesticide formulations and reservoir targeted vaccines for the control of tick species. In addition, we conducted repellency assays with botanical formulations including duration of repellency for a variety active ingredients where information is lacking. We also conducted baseline monitoring of pesticide susceptibility and resistance to inform integrated tick management. Our results demonstrated the high efficacy of 10 percent permethrin topical treatment of white-tailed deer via 4-poster devices in reducing host seeking tick densities and Ehrlichia infection rates of A. americanum. Fipronil-laced bait was readily accepted by white footed mice and other rodent tick borne pathogen reservoirs and reduced juvenile I. scapularis burdens on rodents. Over 80 outdoor contained trials (ARENA) were conducted to evaluate efficacy of synthetic pyrethroids and 25 b exempt products for A. americanum.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2023
Accession Number
AD1213311

Entities

People

  • Laura C. Harrington

Organizations

  • Cornell University

Tags

DTIC Thesaurus Topics

  • Arachnid Bites And Stings
  • Birds
  • Cells
  • Cervidae
  • Environmental Protection
  • Eutrophication
  • Habitats
  • Health Services
  • Lyme Disease
  • Medical Personnel
  • Pest Control
  • Tickborne Diseases
  • Ticks
  • Virus Diseases
  • Viruses
  • Wildlife

Readers

  • Aquatic Ecology
  • Infectious Disease/Epidemiology
  • Vector-Borne Disease and Entomology

Technology Areas

  • Biotechnology