Developing an Angiogenic Therapy to Enhance and Accelerate Repair of Traumatic Bone Defects

Abstract

Our technology works through the stimulation of angiogenesis, an early and critical component of bone repair that subsequently allows for the recruitment of endogenous cell populations and for the optimization of the soft tissue envelope required to enhance bone healing and regeneration. The overarching goal of this proposal is to expedite the healing of traumatic bone defects incurred on the battlefield. We are proposing the advancement of an implantable microparticle technology that will function to accelerate fracture healing and fill large segmental bone defects.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1213465

Entities

People

  • Noah Nelson
  • Steven R. Buchman

Organizations

  • University of Michigan

Tags

DTIC Thesaurus Topics

  • Animal Husbandry
  • Biomedical Research
  • Blast Injuries
  • Buildings And Structures
  • Department Of Defense
  • Electronic Mail
  • Hydrogels
  • Information Operations
  • Instructors
  • Models
  • Pilot Studies
  • Professional Development
  • Research Facilities
  • Soft Tissues
  • Standards
  • Technology Transfer
  • Universities

Readers

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