Nerve Repair with Polyethylene Glycol to Promote Rapid Return of Nerve Function

Abstract

We propose testing the efficacy and safety of a polyethylene glycol (PEG) assisted axonal fusion technique to repair peripheral nerve injuries in humans. After two-year study implementation, we found that our institution continuously worked in a success to deploy this study in our clinical setting, including reliable patient enrollment, implementation of the study protocol into the intraoperative workflow, reliable follow-up of postoperative patients and assessments of drug safety study. So far, we have successfully enrolled 29 patients and completed follow-ups for 11 patients. Preliminary data has been summarized in one manuscript for peer-review.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2023
Accession Number
AD1213941

Entities

People

  • Wesley P Thayer

Organizations

  • Vanderbilt University Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Autografts
  • Biomedical Research
  • Clinical Trials
  • Data Analysis
  • Department Of Defense
  • Dielectric Polymers
  • Employment
  • Information Operations
  • Instructors
  • Maryland
  • Materials
  • Nerve Degeneration
  • Peripheral Nervous System
  • Plastic Surgery
  • Polyethylene Glycols
  • Polyethylenes
  • Safety Analysis
  • Standards
  • Surgery
  • Technology Transfer
  • Training
  • Universities
  • Upper Extremity

Fields of Study

  • Medicine

Readers

  • Distributed Systems and Data Platform Development
  • Nanocomposite Materials Science
  • Neurotrauma and Rehabilitation Medicine.