Confirmation of the Low-Glutamate Diet as a Treatment for Gulf War Illness

Abstract

The proposed research titled "Confirmation of the Low Glutamate Diet as a Treatment for GWI" aims to address the overarching challenge of eliminating the health consequences associated with GWI and revolutionizing treatment. Background: Multiple of the exposures from the Gulf War are known to cause downstream release of glutamate and excitotoxicity, and prior GWI research has also reported evidence of neuroinflammation and oxidative stress as key components of the illness. Excitotoxicity, inflammation, and oxidative stress have the unique ability to influence one another in a self-sustaining manner, forming a neurotoxic triad. Thus, neurological disorders like GWI may require treatments which address all three of these components to result in optimal improvements. The rationale for the proposed clinical trial comes from the very exciting data from our recently completed GWI trial testing the effects of the low glutamate diet on the symptoms of GWI in 40 veterans.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1214515

Entities

People

  • Kathleen F Holton

Organizations

  • American University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Asian Americans
  • Biomedical Research
  • Clinical Trials
  • Department Of Defense
  • Diseases
  • Electronic Mail
  • Glutamates
  • Health Services
  • Hospitals
  • Inflammation
  • Information Operations
  • Maryland
  • Organizational Structure
  • Oxidative Stress
  • Persian Gulf Syndrome
  • Quality Of Life
  • Side Effects
  • Universities

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