A Walking Intervention to Improve Fatigue and Quality of Life in Lupus: A Randomized, Controlled Trial

Abstract

The objective of this project is to implement a simple pedometer-based walking intervention to improve fatigue and quality of life for individuals with lupus. The project addresses two aims: (1) Test the impact of the intervention on activity levels of persons with systemic lupus erythematosus (SLE) using a randomized controlled trial design; and (2) Test the impact of the intervention on fatigue levels and other domains of quality of life, including physical functioning, pain interference, depressive symptoms, cognitive symptoms, social functioning, and sleep disturbance. To date, we have achieved the first two major tasks from the SOW projected to be completed in the first 6 months of the project: IRB approval from both the local IRBs and HRPO, and development of the protocol, including interview protocol, manual of operations, all patient-facing materials, and construction of database for participant screening, tracking, and entry of data. We have made substantial progress in recruiting participants, having reached 50% accrual as of the end of project year 2.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2023
Accession Number
AD1214649

Entities

People

  • Jing Cheng
  • Katie L. Stone
  • Patricia Katz
  • Sarah Patterson

Organizations

  • University of California, San Francisco

Tags

DTIC Thesaurus Topics

  • Arthritis
  • Biomedical Research
  • California
  • Databases
  • Electronic Mail
  • Instructions
  • Intervention
  • Lupus
  • Management Personnel
  • Maryland
  • Materials
  • Medical Personnel
  • Physical Activity
  • Professional Development
  • Quality Control
  • Quality Of Life
  • Rheumatic Diseases
  • Students

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