Internal Standard and Deuterated Solvent Selection: A Crucial Step in PFAS- Based Fluorine-19 (19F) NMR Research

Abstract

This work is vital because it provides researchers with a framework and rationale for selecting the best internal standard and deuterated solvent for their nuclear magnetic resonance (NMR) analysis of per- and polyfluoroalkyl substances (PFAS)-based compounds. Selecting the best internal standard and deuterated solvent will help to ensure that their results are accurate, precise, and sensitive. The internal standard that is chosen can significantly affect the accuracy, precision, sensitivity, and quantification of NMR measurements. Therefore, it is essential to carefully select an internal standard and a matching deuterated solvent that are well-suited for analyzing PFAS compounds.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2023
Accession Number
AD1215045

Entities

People

  • Edith Martinez-guerra
  • Jared S. Cobb
  • P. U. Fernando
  • Samantha N. Sullivan

Organizations

  • Engineer Research and Development Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accuracy
  • Acetic Acid
  • Acetonitrile
  • Acquisition
  • Aqueous Solutions
  • Aromatic Compounds
  • Chemical Shifts
  • Chemical Synthesis
  • Chemistry
  • Fluorine
  • Magnetic Resonance
  • Measurement
  • Nitriles
  • Nuclear Magnetic Resonance
  • Organic Chemistry
  • Organic Compounds
  • Resonance
  • Spectra
  • Spectroscopy
  • Standards

Readers

  • Defense Financial Management and Audit.
  • Organic Chemistry
  • Systems Analysis and Design