Genetic Testing in the Safety Net: Improving Equity in Prostate Cancer Treatment

Abstract

Prostate cancer treatment advances and associated mortality benefits have left behind substantial segments of the US population. African American men have a higher incidence of prostate cancer (203.5 vs. 121.9 per 100,000) and are 2-3 times more likely to die of prostate cancer relative to white men. These disparities are due in large part to the receipt of less effective treatment. Socioeconomic status is a major independent contributor to survival: ten years post-diagnosis, those in the highest socioeconomic strata have a 15 percent higher survival rate compared to those in the lowest strata. Genetic testing to guide treatment decision making is now recommended for certain prostate cancer patients following diagnosis of localized disease and all patients with metastatic disease. Treatment-based disparity gaps may continue to be exacerbated by the underutilization of genetic testing in racial/ethnic minorities and those with low socioeconomic status. The complex underlying reasons for a lack of uptake of genetic testing in vulnerable patient populations remain largely unexplored. Thus, there is a critical need to elucidate the multidimensional reasons for disparities in treatment utilization for minority and low-income men with prostate cancer that reside at the system, provider, and patient levels.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2023
Accession Number
AD1216682

Entities

People

  • Christine Gunn

Organizations

  • Boston Medical Center

Tags

DTIC Thesaurus Topics

  • African Americans
  • Cost Reductions
  • Demography
  • Disparities
  • Genetic Testing
  • Genetics
  • Health Care
  • Health Services
  • Medical Genetics
  • Medical Personnel
  • Minority Groups
  • Neoplasms
  • Oncology
  • Physicians
  • Prostate Cancer
  • Public Health
  • Students

Fields of Study

  • Medicine

Readers

  • Gender and Food Studies
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Prostate Cancer Biology.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech