Intraosseous Antibiotic for Point-of-Care Wound Prophylaxis

Abstract

Combat extremity wounds are severe wounds that often involve multiple tissues and carry the risk of infection. This applied research will leverage skills and techniques already critical to tactical combat casualty care training including the intraosseous catheter placement for the delivery of antibiotic to protect composite tissue wounds from infection even with concomitant use of an extremity tourniquet which may compromise tissue antibiotic concentration distal to the tourniquet. A large animal contaminated, composite tissue model will be used to test if antibiotics delivered by intraosseous catheter will be more effective than standard IV antibiotic delivery for decontaminating wounds. We hypothesize intraosseous antibiotic administration would offer infectious wound protection following severe extremity injury for limb with and without concomitant tourniquet use.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1216904

Entities

People

  • Jessica C. Rivera

Organizations

  • LSU Health Sciences Center New Orleans

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anti-Bacterial Agents
  • Combat Casualty Care
  • Electronic Mail
  • Governments
  • Humanities
  • Infection
  • Internet
  • Local Governments
  • Medical Personnel
  • Patent Applications
  • Point-Of-Care Diagnostic Testing
  • Preventive Medicine
  • Professional Development
  • Standards
  • Students
  • Training

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Trauma or Military Medicine