2021 Prostate Cancer Clinical Consortium Clinical Research Site: University of Washington

Abstract

Purpose: Participate as an active and productive member of the Prostate Cancer Clinical Trial Consortium (PCCTC) throughout the funding period. Scope: This report summarizes total site activities for the University of Washington (UWash) for the funding period 30Sep2022-29Sep2023. Major Progress: UWash was the lead/co-lead site on 15 trials in which we participated during this funding period. Results: UWash accrued 120 patients to PCCTC trials, proposed 4 LOIs, and accrued 15 patients (12.5 percent) from a DAP. Significance: The PCCTC provides a mechanism for participation in early clinical development of novel agents and rapid testing of these agents for the treatment of prostate cancer. Many of the PCCTC trials have challenging entry criteria such as a biopsy of metastatic tissue or complicated pharmacokinetics/pharmacodynamics, and collection of correlative biomarkers. The PCCTC is well positioned to conduct such trials that might not be possible outside of sites that specialize in prostate cancer translational research. Shortening drug development time with better trial design, patient selection, and validation of biomarkers will bring new agents to prostate cancer patients faster, optimize treatment for the individual patient, and avoid treating others with ineffective therapies.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1216906

Entities

People

  • Heather Cheng

Organizations

  • University of Washington

Tags

DTIC Thesaurus Topics

  • Antineoplastic Agents
  • Carcinoma
  • Cardiovascular System
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Genetics
  • Health Services
  • Hematologic Diseases
  • Lymphocytes
  • Medical Personnel
  • Oncology
  • Peptide Growth Factors
  • Proteins

Fields of Study

  • Medicine

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Prostate Cancer Biology.
  • Systems Analysis and Design