Comparison of Flow Rate, Pressure, and Safety Among Pressurized Intraosseous Blood Transfusion Strategies in a Swine (Sus scrofa) Model of Hemorrhagic Shock

Abstract

Intraosseous (IO) infusion is an important vascular access technique used by military first responders to infuse fluids and blood when intravenous (IV) access is difficult or unobtainable.When seconds matter, IO infusion can be set up quickly and started faster than IV in order to rapidly initiate rapid resuscitation. Currently, the optimal IO infusion method is unknown. Unlike IV, IO must overcome the resistance within the medullary space and cancellous bone to achieve clinically meaningful flow; infusion needs to be fast enough to overcome this resistance but must not generate substantially high pressures that cause adverse clinical effects. The purpose of this project is to identify the optimal method of IO infusion to use for critically injured warfighters inthe austere environment. This project is multifaceted and seeks to answer several questions regarding IO access in the prehospital environment: 1) which IO infusion technique provides the fastest flow rate, with minimal complications resulting from high pressures, 2) which IO device is objectively and subjectively best for use in the austere military environment, 3) how IO placement location affects the subsequent flow and pressures generated during infusion.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1218522

Entities

People

  • Jonathan Auten

Organizations

  • Geneva Foundation

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Transfusions
  • Combat Casualty Care
  • Embolism And Thrombosis
  • First Responders
  • Flow Rate
  • Hemorrhagic Shock
  • High Pressure
  • Institutional Review Board
  • Medical Personnel
  • Military Medicine
  • Musculoskeletal Physiology
  • Patient Care
  • Physicians
  • Surgery
  • United States
  • X-Ray Computed Tomography

Readers

  • Cardiovascular Physiology
  • Joint Military Operations and Doctrine.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Space