A Novel Non-Opioid Topical Therapy for Chronic Musculoskeletal Pain
Abstract
The goal of this study is to learn more about the analgesic effects of state-regulated topical cannabinoid products (creams, lotions, salves, etc) and to determine if these topical products are absorbed systemically and can be detected in blood samples. Given that cannabinoid products cannot be brought onto campus, this observational study design utilizes a Mobile Pharmacology Laboratory that will go to study participants' homes to collect data and blood samples. We hypothesize that topical cannabinoids will improve chronic musculoskeletal pain via local tissue interaction, with minimal systemic absorption and no effects on cognition or psychomotor performance. All local regulatory approvals are in place and the Mobile Pharmacology Laboratory is fully equipped and is ready for study visits. However, enrollment has not yet begun due to OHRO request for FDA consultation regarding the potential need for an investigational new drug application and ongoing communication with FDA regarding this issue.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2023
- Accession Number
- AD1219306
Entities
People
- Rachael R. Lynn
Organizations
- University of Colorado Boulder