Multi-Institutional Phase 2/3 Trial of Fresh Frozen Plasma (FFP) in Patients with Moderate to Severe Traumatic Brain Injury (TBI)

Abstract

This study will be a Phase 2/3, randomized, multicenter study performed under Exception From Informed Consent (EFIC) to evaluate the efficacy of administration of FFP in subjects with moderate to severe TBI across eight sites with a history of performing studies under EFIC. The study aims to determine whether administration of 2 units of FFP in patients with moderate to severe TBI due to cerebral contusions attenuates hemorrhagic and/or ischemic progression of brain lesions during the early (24 hours) post- injury period.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1221118

Entities

People

  • Hasan B Alam
  • Sharnia Lashley

Organizations

  • Northwestern University

Tags

Fields of Study

  • Medicine

Readers

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  • Neuroscience
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.