Single Cell Analysis for Forensic Epigenetics (SAFE)

Abstract

The Single-cell Analysis for Forensic Epigenetics (SAFE) project will identify molecular changes in individuals exposed to biological and/or CBRNE threats and could mitigate risks posed by WMD. Specifically, the SAFE project will identify single-cell DNA methylation patterns and chromatin accessibility changes in individuals who have been exposed to high priority threats. The SAFE project also includes acquisition of stabilized RNA and peripheral blood mononuclear cells (PBMCs) from patients exposed to CBRNE threats, and distribution of these biosamples to ACA team members and ECHO performers.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2022
Accession Number
AD1221539

Entities

People

  • Joseph R. Ecker

Organizations

  • Salk Institute for Biological Studies

Tags

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.
  • Munitions and Ordnance Engineering
  • Oncology and Biomarker-Based Cancer Detection.