Assessing the Comparative and Longitudinal Benefits of Vascularized Composite Allotransplantation of the Hand

Abstract

Hand transplantation can restore physical functions, including movement and sensation, and qualitative evidence from our ongoing researchsuggests that hand transplantation can also improve well-being and quality of life (QOL). However, there are risks to receiving handtransplant surgery and patients and doctors need valid information on QOL outcomes to weigh the risks and benefits of hand transplantation.This project will address the FY19 RTRP Focus Areas to (1) define/assess the benefits or value of hand transplant, including the relativevalue of hand transplantation compared to other treatment options and the benefits to social participation and satisfaction, and (2) todetermine how psychosocial functioning changes over time within hand transplant recipients. We will conduct qualitative interviews withparticipants from four different clinical groups: (1) individuals who have undergone hand transplantation, (2) individuals with severe upper-extremity injuries who have undergone limb reconstruction surgery, (3) individuals with upper-extremity amputation who use prostheticdevices, and (4) individuals with upper-extremity amputation who use osseointegrated prosthetic devices. Furthermore, we will develop a setof consensus standardized outcomes measures that can be used at all clinical sites. The overall goal of this qualitative research study is toimprove the methods used for evaluating outcomes after hand transplant surgery, leading to improved clinical decision-making and improved outcomes overall. This information may help hand transplant become a more feasible option for those with hand or arm amputations, which would allow more individuals to resume productive lives as a result.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1222262

Entities

People

  • Callie E. Tyner
  • David S. Tulsky
  • Jerry Slotkin

Organizations

  • University of Delaware

Tags

Fields of Study

  • Medicine

Readers

  • Data Mining and Knowledge Discovery.
  • Neuroscience
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology