Assessing the Comparative and Longitudinal Benefits of Vascularized Composite Allotransplantation of the Hand
Abstract
Hand transplantation can restore physical functions, including movement and sensation, and qualitative evidence from our ongoing research suggests that hand transplantation can also improve well-being and quality of life (QOL). However, there are risks to receiving hand transplant surgery and patients and doctors need valid information on QOL outcomes to weigh the risks and benefits of hand transplantation. This project will address the FY19 RTRP Focus Areas to (1) define/assess the benefits or value of hand transplant, including the relative value of hand transplantation compared to other treatment options and the benefits to social participation and satisfaction, and (2) to determine how psychosocial functioning changes over time within hand transplant recipients. We will conduct qualitative interviews with participants from four different clinical groups: (1) individuals who have undergone hand transplantation, (2) individuals with severe upper-extremity injuries who have undergone limb reconstruction surgery, (3) individuals with upper-extremity amputation who use prosthetic devices, and (4) individuals with upper-extremity amputation who use osseointegrated prosthetic devices. Furthermore, we will develop a set of consensus standardized outcomes measures that can be used at all clinical sites. The overall goal of this qualitative research study is to improve the methods used for evaluating outcomes after hand transplant surgery, leading to improved clinical decision-making and improved outcomes overall. This information may help hand transplant become a more feasible option for those with hand or arm amputations, which would allow more individuals to resume productive lives as a result. In additional to the University of Delaware and Walter Reed National Military Medical Center, the study has been approved at Brigham and Women's Hospital, Johns Hopkins University, the University of Pennsylvania, the University of Louisville, and Massachusetts General Hospital,
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2023
- Accession Number
- AD1222271
Entities
People
- Scott M. Tintle