Novel Metabolites from Crocodile Gut Microbiome
Abstract
The research work has yielded very exciting data that explains why gut microbiome of animals such as crocodile contribute to their hardiness, and this research has the potential to benefit human health and performance. The concept of using bacteria or their metabolites, and/or animal-derived molecules is not unusual, for example, Mutaflor (specific strain of E. coli) is widely used as a probiotic and Captopril, a blood pressure drug was developed from snake venom. These are successful examples and the use of crocodile gut bacteria or their derived molecules to improve performance and well-being of humans is not far-fetched. Although the present research has identified the underlying molecular mechanisms in vitro, future in vivo studies are needed to elucidate their value in the rational development of innovative therapies against cellular stress/gut dysbiosis. Furthermore, the work has led to 9 quality peer-reviewed publications in leading journals during the current year of research activity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 29, 2023
- Accession Number
- AD1222490
Entities
People
- Ruqaiyyah Siddiqui
Organizations
- American University of Sharjah