Harnessing Splenic Adaptations to Improve Diving Capabilities
Abstract
Breath-hold divers have comparatively large spleen volumes (SpVol). The spleen plays a role in clearing bloodborne microparticles (MPs). Pro-inflammatory MPs are associated with decompression sickness. One potential benefit of a larger SpVol may be enhanced clearance of MPs. Repeated apneas and hypoxia exposure increases SpVol, with the magnitude of adaptation modified by thermal stress. We tested the hypothesis that repeated apnea and hypoxia exposure-induced increases in SpVol are correlated with changes in pro-inflammatory MPs.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 10, 2024
- Accession Number
- AD1226517
Entities
People
- Zachary J Schlader
Organizations
- Indiana University