Enriching Vitality and Compressing Risk for Alzheimer's Disease among Aging Veterans with TBI

Abstract

The purpose of this study is to evaluate the efficacy of a novel 3-D gaming intervention (Bandit the Dolphin) on executive functions (e.g., planning), mobility (e.g., walking) and in brain biomarkers linked to risk for Alzheimer's disease. This study will also assess if playing a game that trains to the real world will increase daily activities that in turn promote the brain and body. The scope is to conduct a 12-month randomized controlled trial of individuals with chronic or moderate TBI and evaluate cognitive, physical, psychiatric, physiological, and brain function at baseline, 3-month after the game intervention or healthy aging control arm, followed by a 9-month post intervention assessment. We have currently enrolled and collected data on 13 participants. The most substantial progress during this reporting period is enrolling additional participants, administering the Bandit intervention and Healthy Aging Program, and participants completing the baseline and 3-month follow-up evaluations with MRI. We have also established an additional study site to increase recruitment.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1226974

Entities

People

  • Michelle C. Carlson

Organizations

  • Johns Hopkins University

Tags

Readers

  • Medical Imaging.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.