Long-Term Impact of Military-Relevant Brain Injury Consortium (LIMBIC) Award

Abstract

The Long-Term Impact of Military-Relevant Brain Injury Consortium (LIMBIC) is a coordinated, multicenter, nationwide translational research collaboration that is studying the effects of mild, combat-related TBIs, whether single or repeated, on chronic disabling symptoms, recovery from combat and trauma-related comorbidities, and long-term brain function. This Consortium builds upon the accrued experience of the previous Chronic Effects of Neurotrauma Consortium (CENC) funding cycle (2013-2019), where an Executive Leadership team, a Study Coordinating Center, centralized research Cores (Database and Biostatistics, Imaging, Biomarker), Scientific and Community Advisory Boards, a large, nationwide, multi-level, Prospective Longitudinal Study (PLS) and a multi-site, Retrospective Database Study (RDS) were all established and implemented. These essential elements of CENC have been carried over to LIMBIC and key enhancements of the PLS and RDS have been implemented. The LIMBIC team has completed all regulatory activities, personnel hiring, technical upgrades and documentation adjustments needed for the PLS to initiate follow-up evaluations on all extant participants and also recommence new recruitment of participants, with the easing of COVID-19 research restrictions.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1229226

Entities

People

  • David X. Cifu

Organizations

  • Virginia Commonwealth University

Tags

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.