Stable Mixed Chimerism and Tolerance of Vascularized Composite Allografts via Bcl-2 Inhibition

Abstract

The project aims to develop a clinically applicable nontoxic conditioning regimen with selective Bcl-2 inhibition for induction of mixed chimerism and VCA tolerance.In the first year, the focus was on preparing the field (getting the protocols approved, screening acquiring non-human primates, drugs and reagents) and starting the surgeries .

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1229239

Entities

People

  • Curtis L. Cetrulo, Jr

Organizations

  • Massachusetts General Hospital

Tags

Readers

  • Molecular and Cellular Biochemistry
  • Neuroscience
  • Software Engineering