Stable Mixed Chimerism and Tolerance of Vascularized Composite Allografts via Bcl-2 Inhibition

Abstract

The project aims to develop a clinically applicable nontoxic conditioning regimen with selective Bcl-2 inhibition for induction of mixed chimerism and VCA tolerance. In the first year, the focus was on preparing the field (getting the protocols approved, screening acquiring non-human primates, drugs and reagents) and starting the surgeries.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2023
Accession Number
AD1229240

Entities

People

  • Tatsuo Kawai

Organizations

  • Massachusetts General Hospital

Tags

Readers

  • Combustion science or combustion engineering.
  • Parasitology and Pharmacology of Malaria.
  • Trauma Surgery or Emergency Medicine.