Biophysical Investigations on Additive Manufactured Nanoscale Biosensors and Biological Materials
Abstract
New tools and innovative characterization techniques must be designed to study natural materials and processes like cell signaling, neurons, nervous tissues because of limitations of present technologies. Novel in-situ characterization platform, inspired by the opto-electric interactions occurring in organohalide materials, will be developed. The platform takes advantage of the interaction of photons of well-defined wavelength and power density with biological materials. With this platform, it is possible to extract the physical properties (mobility, work function, density of states, electronic levels) by comparing the obtained data with those from complementary measurements and numerical modelling simulations. This new platform will enable us to: 1) unravel the electronic processes that occur in natural materials and living cells, representing a ground-breaking approach to investigate cellular biology, and 2) design biosensor in order to gauge how the biological material is sensitive to external stimuli such as light, temperature, magnetic fields etc. The research approach will utilize different levels of photo-stimulation and semiconductors with different energy levels and binding properties, and a combination of fully solid state and electrolytic based device platforms. Building upon the fundamental understanding of physical and electronic behavior of natural materials, novel biosensors will be fabricated using nanoprinting techniques and laser annealing.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 16, 2022
- Accession Number
- AD1230195
Entities
People
- Shashank Priya
- Thomas M. Brown
- Zhijian Pei
Organizations
- Pennsylvania State University
- Sapienza University of Rome
- Texas A&M University