Personnel Decontamination Using Zirconium Hydroxide

Abstract

Numerous challenges are associated with decontamination of a military or civilian population that has been exposed to chemical agent contamination. One critical step in mitigating adverse health effects is preventing the absorption of chemical warfare agents into human skin. There has been recent interest in the development of a low-cost, U.S. Food and Drug Administration-cleared, toxic chemical-neutralizing countermeasure for use on unbroken skin. We aimed to meet this goal by exploring the use of zirconium hydroxide as a skin decontaminant. This study characterized the efficacy of Zr(OH)4 in vitro and demonstrated the decontaminant provides similar or better agent removal compared to other established skin decontamination methods.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2024
Accession Number
AD1231029

Entities

People

  • David G. Gehring
  • Janlyn H. Eikenberg
  • Jill L. Ruth
  • Michael J. Chesebrough
  • Michelle L. Sheahy
  • Shawn M. Stevenson
  • Stefanie Q. Smallwood

Organizations

  • Leidos
  • United States Army Combat Capabilities Development Command

Tags

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Neurotoxicology
  • Toxicology/Environmental Toxicology