The Presence of Common Peptide Fragments in the Protein-Allergens of Enterobacteria,
Abstract
The authors examined the protein-allergens isolated from the strains of a number of representatives of intestinal family -- dysentery Flexner 26. E. coli O111, typhoid No. 1203 and paratyphoid B No. 50602 by modified Tsuverkalov's method. The preparations were subjected to enzymatic splitting with crystalline trypsin, and peptide maps of hydrolyzates were obtained by the finger print method. The protein-allergens under study contained in their primary structure fragments, common by peptide composition. This circumstance was a possible cause of cross reactions seen in administration of heterologous allergens to animals sensitized with dysentery vaccine.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 11, 1974
- Accession Number
- ADA000666
Entities
People
- N. I. Shapiro
- N. P. Denisova
Organizations
- National Air and Space Intelligence Center