Sequential Changes of Vascular Ultrastructure in Cerebral Vasospasm: Myonecrosis of Subarachnoid Arteries
Abstract
Cerebral vasospasm following subarachnoid hemorrhage may contribute to morbidity and mortality. The inconsistent therapeutic responses to sympatholytic agents described in the literature raise doubts as to the purely functional nature of the vasoconstriction. This study examines the ultrastructural evolution of vascuolar degeneration of the media in subarachnoid arteries which have been in spasm. The striking changes of myoarchitecture are described; however, the relationship of these findings to aberrations in cerebral blood flow remains to be clarified.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1974
- Accession Number
- ADA000961
Entities
People
- J. L. Parker
- J. M. Fein
- L. J. Parkhurst
- W. J. Flor
Organizations
- Armed Forces Radiobiology Research Institute