Mammalian Cold Receptor Afferents: Role of an Electrogenic Sodium Pump in Sensory Transduction

Abstract

The responses of specific cold-sensitive afferents and cold-sensitive mechano-receptors were recorded from rat pudendal nerve. A local infiltration of ouabain into the region of the afferent terminals caused a dramatic increase in discharge at warm temperatures without significant effect on discharge in the cold. These results suggest that an electrogenic sodium pump is the generator potential mechanism imparting cold sensitivity. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1974
Accession Number
ADA000963

Entities

People

  • D. O. Carpenter
  • Fr.-k. Pierau
  • P. J. Torrey

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Body Temperature
  • Cells
  • Climate Change
  • Dynamic Response
  • Frequency
  • Generators
  • High Temperature
  • Laboratory Animals
  • Membrane Potentials
  • Nerves
  • Neurons
  • Peripheral Nervous System
  • Sensitivity
  • Sensory Receptor Cells
  • Temperature Coefficients
  • Terminals

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  • Neuroscience