The Role of Allergy in the Pathogenesis of Nasal Polyposis (Clinical, Biochemical and Immunological Investigations),

Abstract

Moderately pronounced shifts were noted in the blood serum proteinogram in nasal polyposis patients - an increase in the content of gamma-globulins and a decrease in the content of beta-globulins. Hyperglobulinemia was ascertained in polypous fluid as a result of a considerable increase in gamma- and a decrease in beta-globulins. Accumulation takes place in nasal polyps, and possibly also the formation of gamma-globulins. The histamine metabolism was disrupted in nasal polyposis patients, which is expressed in variations in the indices of histamine metabolism - in an increase in the histamine content, a reduction in histaminase, histamine inhibitors, histaminopexic index, and also in the appearance in a number of patients of stimulators both in the blood and in the polypous fluid.

Document Details

Document Type
Technical Report
Publication Date
Nov 13, 1974
Accession Number
ADA001853

Entities

People

  • G. N. Popova

Organizations

  • National Air and Space Intelligence Center

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Serum
  • Chemical Compounds
  • Gamma Globulin
  • Globulins
  • Histamine
  • Inhibitors
  • Metabolism
  • Nose Diseases
  • Pathogenesis

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Infectious Disease/Epidemiology
  • Oncology and Biomarker-Based Cancer Detection.