Nature and Control of Side-Reactions Due to Diethylcarbamazine in the Treatment of Malayan Filariasis.
Abstract
The chemotherapy against human filariasis has developed since Santiago-Stevenson (1947) had reported that 1-diethylcarbamyl-4-methyl-piperazine hydrochloride has an activity of the rapid disappearance of microfilaria from the peripheral blood. And many trials of mass treatment by this compound have ever been made by the investigators all over the world. However, because of the adverse reactions after drug administration, it is urgently necessitated to know the nature and control of these reactions, particularly in the treatment of malayan filariasis, in order to bring the successful results in the chemotherapeutic control measure of this nematodiasis. Studies on several dose schedules and the histopathology of adverse reactions are discussed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 21, 1974
- Accession Number
- ADA002797
Entities
People
- Byong-seol Seo
Organizations
- Seoul National University