The Effect of Certain Antibiotics, 6-Mercaptopurine and Cortisone on the Course of Active Anaphylactic Shock in Guinea Pigs,

Abstract

The effect of aurantin, oxytetracycline and aurantin combination with oxytetracycline as well as 6-mercaptopurine and cortisone on anaphylactic shock in guinea pigs was studied. It was found, that only cortisone used for prolong periods of time during sensitization preceded with its administration several days before sensitization protected more than 50 per cent of sensitized guinea pigs from fatal anaphylactic shock. The other preparations had no protecting effect on sensitized animals with respect to death from anaphylactic shock.

Document Details

Document Type
Technical Report
Publication Date
Nov 18, 1974
Accession Number
ADA002804

Entities

People

  • E. I. Fedorov
  • Kh. Kh. Planeles

Organizations

  • National Air and Space Intelligence Center

Tags

DTIC Thesaurus Topics

  • Animals
  • Anti-Bacterial Agents
  • Rodents
  • Shock (Pathology)

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Immunology